**Irritable Bowel Syndrome with Diarrhea (IBS-D)** is a stomach condition causing tummy pain and loose stools. This study tests a medicine called **eluxadoline** in children aged 6-17 years with IBS-D. The study checks how well the medicine works, its safety, and how the body processes it. Right now, only kids aged 6-11 can join because the older age group is full.

Key Points:

• The study involves several visits and assessments, including a screening visit and a randomization visit.
• Participants must not have certain health conditions, like severe constipation or gallbladder issues.
• Children must be able to use an electronic diary or have help from a parent or guardian.

To join, kids need to have a specific type of IBS-D and not have other digestive problems. Parents must agree and sign a consent form before any study-related activities begin. The study is important because it helps doctors learn more about treating IBS-D in children safely and effectively.