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Open-Label Study of AXS-07 for the Acute Treatment of Migraine in Adults With a Prior Inadequate Response to an Oral CGRP Inhibitor (EMERGE)

Study on AXS-07 for migraine relief in adults with previous treatment issues.

Recruiting
18 years and older
All
Phase 3

This study tests a medicine called AXS-07 for adults who have migraines. A migraine is a bad headache that can make you feel sick or see flashing lights. The study is "open-label," which means everyone knows they are taking AXS-07. It is for people who have tried other migraine medicines called oral CGRP inhibitors and they didn't help enough. CGRP inhibitors are pills that try to stop migraines by blocking a chemical called CGRP.

If you join, you will take AXS-07 for up to 8 weeks at home to see if it helps with your next 4 migraine attacks. To be in the study, you need to have migraines already and have tried CGRP inhibitors before. You cannot join if you are pregnant, breastfeeding, or planning to get pregnant soon. Also, you cannot have used any other new medicine in the last 30 days.

  • The study lasts up to 8 weeks.
  • You will self-treat up to 4 migraines at home.
  • No new migraine treatments 30 days prior to starting.
Study details
    Migraine

NCT05550207

Axsome Therapeutics, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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