Study Summary: This study is for kids under 13 with sickle cell disease (SCD), a condition where red blood cells are shaped like crescents, making it hard for them to carry oxygen well. The study involves a special treatment called a hematopoietic stem cell transplantation (HSCT). In this treatment, healthy cells from a sibling's bone marrow (a soft part inside bones) are given to the sick child. Before this, kids will get special medicines called conditioning to prepare their bodies.
Participants will spend 4-6 weeks in the hospital and continue with regular check-ups for 6 to 12 months after. Researchers will watch the kids for 2 years to see how they do.
- Time Commitment: Hospital stay 4-6 weeks, followed by 6-12 months of clinic visits.
- Eligibility: Children under 13 with SCD and a healthy sibling donor.
- Goal: To see if this treatment helps kids with SCD live healthier lives.
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