Image

Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation

Testing sibling stem cell matching for treatment compatibility.

Recruiting
2-13 years
All
Phase 2

Study Summary: This study is for kids under 13 with sickle cell disease (SCD), a condition where red blood cells are shaped like crescents, making it hard for them to carry oxygen well. The study involves a special treatment called a hematopoietic stem cell transplantation (HSCT). In this treatment, healthy cells from a sibling's bone marrow (a soft part inside bones) are given to the sick child. Before this, kids will get special medicines called conditioning to prepare their bodies.

Participants will spend 4-6 weeks in the hospital and continue with regular check-ups for 6 to 12 months after. Researchers will watch the kids for 2 years to see how they do.

  • Time Commitment: Hospital stay 4-6 weeks, followed by 6-12 months of clinic visits.
  • Eligibility: Children under 13 with SCD and a healthy sibling donor.
  • Goal: To see if this treatment helps kids with SCD live healthier lives.
Study details
    Sickle Cell Disease

NCT04018937

Emory University

12 October 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.