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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

Exploring shorter chemo-immunotherapy for early-stage triple-negative breast cancer.

Recruiting
18 years and older
All
Phase 3

This study is for people with a type of breast cancer called Triple Negative Breast Cancer (TNBC). The study is seeing if a shorter chemotherapy (chemo) without a drug called anthracycline is as good as the usual chemo. Chemo is medicine that helps stop cancer from growing. Medicines in this study include paclitaxel, carboplatin, cyclophosphamide, and docetaxel. A new medicine called pembrolizumab helps the immune system fight cancer.

Key Points:

  • The study lasts up to 5 years with check-ups every 6 months in the first 2 years.
  • Participants might get different medicines depending on which group they are placed in.
  • Participants may provide blood samples and answer questions about their health.

You can join this study if you have TNBC, are 18 years or older, and meet other health criteria. You should not have received certain treatments before or have severe allergies to the study medicines. Joining this study could help doctors learn if a shorter chemo is just as good and possibly easier for patients. Participants will have regular medical check-ups to ensure safety. Always talk to your doctor before joining any study to understand the benefits and risks.

Study details
    Anatomic Stage I Breast Cancer AJCC v8
    Anatomic Stage II Breast Cancer AJCC v8
    Anatomic Stage IIIA Breast Cancer AJCC v8
    Anatomic Stage IIIB Breast Cancer AJCC v8
    Early Stage Triple-Negative Breast Carcinoma

NCT05929768

SWOG Cancer Research Network

13 December 2024

Step 1 Get in touch with the nearest study center
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  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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