The Pediatric MATCH Screening Trial aims to treat kids with advanced tumors or lymphomas using genetic testing. A tumor is a lump of abnormal cells growing in the body. Genetic testing looks at the genes in these tumor cells to find changes called mutations. These mutations might respond better to specific treatments that target them, possibly helping doctors choose better treatments for these kids.
Key Points:
- Participants must be between 12 months and 21 years old with specific types of tumors.
- The study involves genetic testing and targeted treatments over two years unless issues arise.
- Regular follow-ups will happen after treatment is completed.
Doctors will first check if your child has specific genetic mutations by taking a sample of their tumor. If they do, they might receive a special treatment that targets that mutation. The study tries different treatments to see which work best for different genetic mutations. It's important to note that participation may involve various tests like biopsies, scans, and blood samples, and the treatments can last up to 2 years. All these efforts aim to find better ways to treat these difficult cancers in kids.