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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Join a study on monitoring atrial fibrillation with continuous rhythm evaluation.

Recruiting
22-85 years
All
Phase 3

REACT-AF is a study for people aged 22-85 with a type of irregular heartbeat called Atrial Fibrillation (AF). This study compares two approaches using blood thinners called Direct Oral Anticoagulants (DOACs). One approach is to take DOACs continuously, and the other is to take them only for 30 days when the AF is detected by a Smart Watch. If you have a moderate risk of stroke, this study might be for you. The stroke risk is calculated using a score called CHA2DS2-VASc. Participants need to wear a smart watch for at least 14 hours a day and must have a compatible smartphone. The study will last up to 60 months, or 5 years.

  • Participants must be willing to wear a smart watch and use a smartphone.
  • The study might last up to 5 years, with regular check-ins.
  • Participants should not be on other strong blood thinners like warfarin.
Study details
    Atrial Fibrillation

NCT05836987

Johns Hopkins University

9 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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