Image

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Exploring a new treatment for children with NGGCT brain tumors.

Recruiting
3-29 years
All
Phase 2

This study is for children and young adults with a brain tumor called NGGCT. NGGCT stands for non-germinomatous germ cell tumors. These tumors are in the brain but haven't spread to other parts of the body. The study aims to find the best way to combine chemotherapy and radiation therapy based on how patients respond to initial treatment. Chemotherapy uses drugs to kill cancer cells or stop them from growing, while radiation therapy uses high-energy rays to do the same. The study will help decide if patients need more chemotherapy, radiation, or both, depending on how their tumors react to the first treatment.

Key Points:

  • **Study Length**: Patients will be followed for up to 10 years after treatment.
  • **Treatment**: Includes chemotherapy and possibly radiation therapy or a stem cell transplant.
  • **Eligibility**: Patients aged 3 to 30 with specific types of brain tumors can join.

After initial chemotherapy, patients may receive different treatments based on their tumor response. This personalized approach aims to reduce side effects and improve outcomes.

Study details
    Central Nervous System Nongerminomatous Germ Cell Tumor
    Choriocarcinoma
    Embryonal Carcinoma
    Immature Teratoma
    Malignant Teratoma
    Mixed Germ Cell Tumor
    Pineal Region Germ Cell Tumor
    Pineal Region Immature Teratoma
    Pineal Region Yolk Sac Tumor
    Suprasellar Germ Cell Tumor

NCT04684368

Children's Oncology Group

16 February 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.