Image

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

Testing Ianalumab vs. placebo with standard treatment for active lupus nephritis.

Recruiting
18 years and older
All
Phase 3

This research study tests a medicine called ianalumab given as a shot under the skin to help treat lupus nephritis (LN), a kidney disease caused by lupus. The medicine will be compared to a placebo, which is a treatment with no active medicine. People in the study will also receive standard care (SoC) treatment. Participants will receive ianalumab every 4 weeks or every 12 weeks.

To join the study, you must be 18 or older, weigh at least 35 kg, and have a confirmed diagnosis of lupus. You also need to have active LN, which will be confirmed by a kidney test called a biopsy. If you have a serious kidney problem or have used specific medicines recently, you may not be able to join.

  • The study will last several months with regular doctor visits for treatments and check-ups.
  • Participants may receive a new treatment or a placebo, along with their regular medication.
  • There may be some risks, like side effects from the medicine or the placebo.

Discuss with your doctor if this study is right for you.

Study details
    Lupus Nephritis

NCT05126277

Novartis Pharmaceuticals

2 February 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.