Image

SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis

SAFE Study: Checking safety of aPCC with Emicizumab use.

Recruiting
6 years and older
All
Phase 3

SAFE Study is looking at the safety and effectiveness of a drug called aPCC for people with hemophilia A, a condition where the blood doesn't clot well. Some people with hemophilia A develop inhibitors, which are blockers that make treatment harder. These patients are already on a medicine named emicizumab to help prevent bleeding. The study is for those who have serious bleeding episodes or need special procedures. Participants must be at least 6 years old, have certain levels of blood components, and meet other health criteria. The study will not include anyone with other bleeding disorders, certain health conditions, or those taking specific medications.

  • The study requires participants to have regular check-ups and tests.
  • Participants will receive a personalized dose of aPCC based on their needs.
  • Risks might include allergic reactions or other side effects.

If you think you might fit the criteria, you and your caregiver will need to provide consent to join the study. It's important to discuss with your doctor to see if this study could be beneficial for your condition.

Study details
    Hemophilia A

NCT04563520

Emory University

5 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.