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A Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid Tumors

Exploring Navicixizumab for advanced solid tumors in patients.

Recruiting
18 years and older
All
Phase 2
This clinical study is exploring the effects of a new drug, **navicixizumab**, either alone or with other cancer treatments, on certain advanced cancers. The study involves four groups of patients with different types of cancer, including **CRC** (colon/rectal cancer), **gastric and GEJ cancer** (stomach and gastroesophageal junction cancer), **TNBC** (triple-negative breast cancer), and **platinum-resistant ovarian cancer**. Participants will receive treatment in **4-week cycles** and undergo regular check-ups, including heart and tumor monitoring. The study will continue until the tumor grows, side effects become intolerable, or the patient or doctor decides to stop. **CT scans** are used to track tumor progress, and heart function is checked using **echocardiograms**. Key Points:
  • Participants must be at least 18 years old and have specific types of advanced cancer.
  • The study involves regular visits, heart and tumor monitoring, and follow-up calls after treatment ends.
  • Female participants must use effective birth control and have a negative pregnancy test to join.
Study details
    Colorectal Cancer
    Triple Negative Breast Cancer
    Gastric Cancer
    Ovarian Cancer

NCT05453825

OncXerna Theraputics, Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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