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Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD

Join a study testing new treatment for GERD with PPIs.

Recruiting
18-75 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study tests a new treatment for GERD (Gastroesophageal Reflux Disease), a condition causing heartburn. The study will compare a drug called MHS-1031, which is a special type of carbohydrate known as a prebiotic, to a placebo, which is a pill with no real medicine. Participants must already be taking PPIs (Proton Pump Inhibitors) like omeprazole to reduce stomach acid, and they should have some improvement in their symptoms.

The study is double-blind, meaning neither the doctors nor the participants know who is getting the real drug or the placebo. Participants will complete online surveys to see how many days they are free from heartburn.

  • Study Length: This study includes three phases and lasts around 8 weeks.
  • Requirements: Participants need to fill out online questionnaires daily.
  • Compensation: Participants may receive compensation for their time and effort.

Those interested should be between 18-75 years old, have internet access, and be on a stable dose of PPIs. People with certain medical conditions or those unable to follow the study rules will not be eligible to participate.

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Study details
    Gastroesophageal Reflux

NCT05556824

Microbiome Health Sciences

2 March 2025

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Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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