This study looks at how well a medicine called **semaglutide** can help teenagers lose weight and keep it off. Semaglutide is given as a **weekly injection** with a thin needle in the stomach, thighs, or upper arms. All teenagers in the study will get this treatment for at least **3 years**. The study is for teens **aged 12 to 14 years** who are heavier than most kids their age.

To join, you need to sign forms saying you understand what the study is about. You can't join if you've had certain weight-loss treatments before or if you have some specific health conditions, like diabetes.

• The study lasts a minimum of 3 years.
• All participants will receive semaglutide injections weekly.
• Eligibility requires a BMI over the 95th percentile and body weight over 60 kg.