The PediDOSE study aims to improve how paramedics treat seizures in children during ambulance rides. A seizure is when a person has uncontrolled movements and might not be aware of what's happening. Paramedics usually give a medicine called midazolam to help stop seizures. However, sometimes the dose isn't right, which can delay stopping the seizure. This study tests giving standardized doses based on the child's age, either as a shot or nasal spray, instead of calculating each time.
The study will be conducted in 20 cities, and paramedic protocols will be changed gradually and randomly. Researchers want to see if this new method helps more kids stop seizing by the time they reach the hospital and is just as safe as the current method. Safety is crucial because too much midazolam can affect breathing.
- Study involves changing treatment in 20 cities.
- It's important to ensure the new method is safe.
- Participation includes children actively seizing during ambulance care.
If successful, this could change how seizures in children are treated in ambulances everywhere.