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Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma

Exploring new treatments for high-risk myeloma with a clinical trial.

Recruiting
18 years and older
All
Phase 2

This study tests a new treatment for high-risk myeloma, a type of blood cancer. The treatment uses three medicines: belantamab mafodotin, a special antibody that delivers chemotherapy to cancer cells; pomalidomide, a drug that stops cancer cells from growing; and dexamethasone, which reduces inflammation. This treatment aims to kill more cancer cells.

Participants will receive belantamab mafodotin through an IV once every two cycles (56 days), pomalidomide as a daily pill for 21 days each cycle (28 days), and dexamethasone as a pill on specific days. The study lasts until the cancer stops responding or side effects become too severe. Afterward, patients will have check-ups every 3 months.

  • Length and Visits: Treatment cycles are 28 days, with regular follow-up visits.
  • Eligibility: Patients must have recently undergone a stem cell transplant and meet specific health criteria.
  • Risks: Possible side effects include eye problems, liver issues, or infections. Contact lenses are not allowed during the study.
Study details
    Plasma Cell Myeloma

NCT05208307

Emory University

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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