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National Adaptive Trial for PTSD Related Insomnia

Join a PTSD-related insomnia trial to explore potential treatments.

Recruiting
18-75 years
All
Phase 3

Veterans with PTSD often struggle with insomnia, which means they have trouble sleeping or have frequent nightmares. This study aims to find out if two medications, trazodone and eszopiclone, can help. PTSD stands for Post-Traumatic Stress Disorder, a type of strong anxiety that can happen after a very stressful event. Symptoms include bad dreams, feeling angry, and having a hard time focusing. The study compares these medications to a placebo, a pill with no medicine in it, to see if they help with sleep. It's a 12-week study with different groups trying different treatments. Researchers will check how well each treatment works using something called the Insomnia Severity Index (ISI). Veterans can join if they're 18 to 75 years old and have PTSD from military service. Participants must agree to follow study rules and be available for 17 weeks. They can't join if they're in another study or have had certain medical issues recently. This research helps find better ways to treat sleep problems in Veterans with PTSD.

  • The study lasts about 17 weeks including screening and assessment.
  • Participants will receive either trazodone, eszopiclone, or a placebo.
  • The study aims to improve sleep quality in Veterans with PTSD.
Study details
    Insomnia

NCT03668041

VA Office of Research and Development

5 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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