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A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity

Exploring new Tirzepatide doses for Type 2 Diabetes and Obesity.

Recruiting
18-75 years
All
Phase 2

This study wants to find out how safe and effective a new medicine, called tirzepatide, is for people with Type 2 Diabetes (T2D) and obesity who are already taking metformin. Metformin is a common medicine for diabetes. The study will last about 89 weeks, which is a little over 1.5 years. You will have a screening period of up to 5 weeks to see if you can join. The main results will be looked at around Week 44, and the study will continue until Week 80. There will be a safety check about 4 weeks after you finish taking the medicine.

  • You need to visit the study site multiple times over 89 weeks.
  • You must already be using metformin and have a BMI of 35 or more.
  • People with Type 1 Diabetes or certain health issues cannot join.

Eligibility: You should have a stable body weight and have been using metformin regularly. Exclusions: If you have Type 1 Diabetes, certain heart conditions, or are using weight loss products, you cannot participate.

Study details
    Type 2 Diabetes
    Obesity

NCT06037252

Eli Lilly and Company

9 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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