Basal Cell Carcinoma (BCC) is a common type of skin cancer. This study is testing a new treatment called VP-315, which is injected directly into the cancer spots on the skin. The study will involve about 80 adults with BCC, and it will take place at several locations. The goal is to find out how safe the treatment is and how well it works.

People in the study will get the treatment for 3 days each week, followed by 4 days with no treatment. The study will last for several weeks, and participants will need to visit the study site regularly to get the injections and have their progress checked.

• The study involves multiple visits and regular injections.
• Participants should avoid certain skin products and sunlight during the study.
• Participants must be willing to have surgery on the BCC spots after the study ends.

Before joining, participants must meet specific criteria, such as being 18 years or older and having BCC spots that can be biopsied. Certain health conditions and treatments may exclude someone from participating. Participants will need to use effective birth control during the study and for 4 weeks after the last treatment. They must also agree to photographs of their skin being taken for study purposes.