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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

Studying Dexrazoxane's impact on heart health after cancer treatment.

Recruiting
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Phase N/A

This study looks at how a medicine called dexrazoxane hydrochloride affects certain substances in the blood called biomarkers, which are linked to heart problems like cardiomyopathy and heart failure after cancer treatment. Dexrazoxane hydrochloride (DRZ) is a drug that might help protect the heart. The study will compare cancer patients who took DRZ with those who did not, looking at their heart health markers.

Patients will undergo tests, including a physical exam, echocardiogram (an ultrasound test for the heart), blood tests, and a 6-minute walk test. They will also answer questionnaires about quality of life, family history, and physical activity.

  • Participants must have had cancer treatment and be in remission or have relapsed.
  • The study is open for those who have medical records available and meet the criteria.
  • Patients will need to sign a consent form to participate.

This study will help doctors understand if DRZ can reduce heart problems in cancer survivors and improve their long-term health.

Study details
    Hodgkin Lymphoma in Remission
    Leukemia in Remission
    Lymphoblastic Lymphoma
    Osteosarcoma
    Recurrent Leukemia
    Recurrent Lymphoma
    Recurrent Malignant Neoplasm

NCT01790152

Children's Oncology Group

13 December 2024

Step 1 Get in touch with the nearest study center
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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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