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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Study testing BGB-16673 for B-cell cancer patients.

Recruiting
18 years and older
All
Phase 1/2

Study Overview: This research aims to find the best dose of a new drug called BGB-16673 for people with certain blood cancers. The study has two parts: Phase 1 to test different doses and Phase 2 to check how well the chosen dose works.

Eligibility: To join, participants must have one of these cancers: Marginal Zone Lymphoma (MZL), Follicular Lymphoma (FL), or others like them. They should have tried similar treatments before but have not responded well. Participants must be physically able, as per the Eastern Cooperative Oncology Group (ECOG) Performance Status, which is a scale from 0 (fully active) to 2 (capable of self-care but unable to work). People with other active cancers or health issues affecting the brain or nervous system cannot participate.

  • Length: Study is divided into two phases, exact duration per phase not specified.
  • Visits: Participants may need to visit the clinic several times for assessments and monitoring.
  • Risks: Possible side effects as with any cancer treatment; specific risks will be discussed with you.
Study details
    B-cell Malignancy
    Marginal Zone Lymphoma
    Follicular Lymphoma
    Non-Hodgkin Lymphoma
    Waldenström Macroglobulinemia
    Chronic Lymphocytic Leukemia
    Small Lymphocytic Lymphoma
    Mantle Cell Lymphoma
    Diffuse Large B Cell Lymphoma

NCT05006716

BeiGene

16 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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