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Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension

Join an ongoing study for adults with high cholesterol.

Recruiting
18 years and older
All
Phase 3
Study Summary

This study is for people with high cholesterol, which means they have too much fat in their blood. We are looking at a medicine called enlicitide decanoate. This is an oral PCSK9 inhibitor, a type of medicine that helps lower cholesterol by blocking a protein called PCSK9. To join this study, you must have finished a previous study with enlicitide decanoate. You should have also followed the study rules well and not stopped the medicine early.

If you had a bad reaction in the last study, you won't be able to join. Also, you can't join if you plan to start a different cholesterol medicine or if you're in another clinical study right now.

  • Participants must have completed a related study before joining.
  • You must have followed the previous study rules well.
  • You can't join if you had serious side effects in the last study.
Study details
    Hypercholesterolemia

NCT06492291

Merck Sharp & Dohme LLC

2 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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