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Study to Determine the Prevalence of Hypercortisolism in Patients With Type 2 Diabetes and Treatment With Korlym® (Mifepristone) (CATALYST)

Study checks cortisol levels in Type 2 diabetes patients using Korlym®.

Recruiting
18-80 years
All
Phase 4

Study Overview: This research is looking at people with type 2 diabetes (T2D) that is hard to control. It will see how many of them also have a condition called hypercortisolism, which is when the body makes too much of the hormone cortisol. The study has two parts. The first part doesn't involve treatment and will check if people with hard-to-control diabetes have hypercortisolism. The second part includes treatment with a drug called mifepristone, which will be tested to see if it helps with hypercortisolism in these patients.

Key Points:

  • The study takes place at about 30 sites in the US and involves two parts: screening and treatment.
  • In the treatment phase, participants may get mifepristone or a placebo (a fake treatment) to test its effects.
  • Eligibility requires having specific diabetes conditions and other health criteria; some medications and conditions might exclude you.

Note: If you have type 1 diabetes, are pregnant, or have certain health issues, you may not qualify.

Study details
    Hypercortisolism
    Diabetes Mellitus
    Type 2

NCT05772169

Corcept Therapeutics

12 October 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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