This study looks at how well a medicine called aticaprant works with antidepressants to stop depression symptoms from coming back. Depression is a feeling of deep sadness or not enjoying things. Aticaprant is taken with antidepressants like SSRI or SNRI. SSRI stands for Selective Serotonin Reuptake Inhibitor, and SNRI stands for Serotonin-Norepinephrine Reuptake Inhibitor. These medicines help improve mood.
To join this study, you need to be healthy based on medical tests and have a type of depression called Major Depressive Disorder (MDD). You should also have a symptom called anhedonia, which means not finding pleasure in things. You can't join if you haven't responded to at least two antidepressant treatments, have serious alcohol or drug problems, or have thoughts of harming yourself or others.
Key Points:- The study requires a stable response to aticaprant before participation.
- Participants must be free from severe substance abuse and follow study rules.
- There is ongoing assessment of health stability through medical tests.