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Safety, Reactogenicity and Immunogenicity of HB-502 and HB-501 Versus Placebo in People With HIV on Suppressive ART

Studying new HIV vaccines' safety and effects in people on ART.

Recruiting
18-65 years
All
Phase 1

This study is for people with HIV (Human Immunodeficiency Virus) who are on ART (Antiretroviral Treatment) to see if a new treatment, called HB-502 and HB-501, is safe and if it helps the body fight HIV. ART helps control HIV but might not work forever because the virus can start growing again. This study tests if the new treatment can teach the immune system to better recognize and fight HIV. Participants will get an injection into their muscle every 8 weeks for 24 weeks, followed by 24 more weeks of check-ups. The treatment uses special viruses, known as vectors, which are safe and help deliver parts of the HIV virus to the body to help it recognize the virus.

  • Study duration is 24 weeks of treatment plus 24 weeks of follow-up.
  • Participants receive an injection every 8 weeks for a total of 4 doses.
  • Approximately 30 people will be part of this study.
Study details
    Human Immunodeficiency Virus (HIV) Infection

NCT06430905

Hookipa Biotech GmbH

22 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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