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NATIENS: Optimal Management and Mechanisms of SJS/TEN

Clinical trial for managing and understanding SJS/TEN.

Recruiting
18 years and older
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

The NATIENS study is a research project focusing on improving treatments for Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). These are serious skin conditions where the skin peels off, often caused by a drug reaction. The study compares the use of a drug called etanercept, which affects the immune system, with regular care to see which helps skin heal faster. Researchers will collect samples like skin and blood to learn more about SJS/TEN and find ways to prevent or treat it better.

Key Points:

  • The study will last 4 years and involve 150 patients.
  • Participants will help scientists understand more about SJS/TEN and test a new treatment option.
  • Samples taken will help predict the risk and outcome of SJS/TEN and improve future treatments.
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Study details
    Stevens-Johnson Syndrome
    Toxic Epidermal Necrolyses

NCT02987257

Vanderbilt University Medical Center

13 December 2024

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