This study is for people with HIV who have stable, low levels of the virus in their blood, referred to as "virologically suppressed" (HIV-1 RNA < 50 copies/mL). It aims to compare two treatment regimens: a new weekly pill made of islatravir and lenacapavir (ISL/LEN), versus the standard daily treatment, bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF). The goal is to see if the weekly pill is as effective as the daily one over 48 weeks.
- Duration: The study lasts 48 weeks.
- Eligibility: You must have been on B/F/TAF for at least 6 months with stable virus levels. You cannot have had past treatment failures or certain infections like hepatitis B or active hepatitis C.
- Considerations: Participants will be monitored for safety and effectiveness of the new weekly regimen.
If you are eligible, participation involves regular health check-ups and following the study's guidelines on medication. It's important to discuss with your doctor if joining this study is right for you.