MyeloMATCH Study Summary: This study is for people with myeloid cancer, like acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). It helps doctors decide if a patient should join a special treatment study or continue with their regular treatment. Doctors will test a patient's bone marrow and blood to look for special markers. These markers help doctors understand the cancer better and choose the best treatment. The study uses these tests to quickly match patients to the right treatment plan, or they continue with their usual care if no match is found.

• Participants must be 18 years or older and not have had treatment for AML or MDS before joining.
• The study involves regular bone marrow and blood tests to monitor progress.
• Participants may need to travel for specific treatment studies if their current location doesn't offer it.

Before joining, participants will need to give consent and agree to have their medical samples used for research. This study aims to improve cancer treatment by better understanding how cancers respond to different therapies. Participants can help advance research while potentially receiving targeted care for their condition.