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A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)

Study on Efinopegdutide for liver cirrhosis from steatohepatitis.

Recruiting
18-80 years
All
Phase 2

This study is for people with compensated cirrhosis, a liver condition where the liver is still working despite damage. It is caused by metabolic dysfunction-associated steatohepatitis (MASH), a condition where fat buildup leads to liver inflammation and scarring. The study tests if the medicine efinopegdutide can reduce liver fat, inflammation, and scarring. Researchers will also check the safety and how well people can handle this medication.

  • Participants must have MASH and may or may not have controlled type 2 diabetes.
  • People with other liver diseases, type 1 diabetes, or recent major illnesses cannot join.
  • The study will involve regular visits, and participants may receive compensation.

If you are interested and meet the criteria, you can consider participating in this research to help find a treatment for MASH. If you are unsure about your eligibility or have questions about the study, contact the research team for more details.

Study details
    Non-alcoholic Fatty Liver Disease
    Nonalcoholic Steatohepatitis
    NAFLD
    Metabolic Dysfunction-associated Steatotic Liver Disease
    Metabolic Dysfunction-associated Steatohepatitis

NCT06465186

Merck Sharp & Dohme LLC

2 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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