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A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

Studying long-term safety of Tolebrutinib for Multiple Sclerosis patients.

Recruiting
18 years and older
All
Phase 3

This study is about testing the long-term safety of a drug called tolebrutinib in adults with different forms of Multiple Sclerosis (MS). MS is a condition where the immune system mistakenly attacks the brain and spinal cord. This study is for people who were already part of earlier trials.

Open-label (OL) means participants know what treatment they are getting. People from earlier studies will either continue or start taking tolebrutinib. If they were taking another drug called teriflunomide, they might need to stop it before starting tolebrutinib.

Participants will take tolebrutinib for about 3 years. To join, they must have been part of previous trials and meet specific health criteria. They can't join if they have certain infections, liver issues, or if they drink too much alcohol.

  • Study duration: around 3 years of taking tolebrutinib.
  • Participants must have been in previous MS trials.
  • Exclusion includes significant health issues like infections or liver disease.

This information is important for deciding if this study is right for you. Always discuss with your doctor before joining any study.

Study details
    Relapsing Multiple Sclerosis
    Secondary Progressive Multiple Sclerosis
    Progressive Relapsing Multiple Sclerosis

NCT06372145

Sanofi

15 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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