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A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

Study on new treatment for KRAS G12D-mutant solid tumors.

Recruiting
18 years and older
All
Phase 1

This study will explore how safe and effective a new drug, LY3962673, is for people with certain types of cancer. Specifically, it targets cancers with the KRAS G12D mutation, which is a change in the genes that can make cells grow out of control. The study will last about 5 years and will include people with advanced cancers that have spread or cannot be removed by surgery.

People can join this study if they have had at least one round of chemotherapy before and their cancer has the KRAS G12D mutation. Participants should not have serious heart problems or active infections like hepatitis. They should also not have severe side effects from previous treatments.

  • This study will last approximately 5 years.
  • Participants will receive a new drug, LY3962673, alone or with other chemotherapy drugs.
  • Participants need to have specific mutations in their cancer and have previously undergone chemotherapy.

Joining a study like this can help doctors learn more about treating KRAS G12D-mutant cancers and may offer potential benefits to participants, but it may also involve risks and side effects from the treatment.

Study details
    Pancreatic Ductal Adenocarcinoma
    Non-small Cell Lung Cancer
    Colorectal Cancer

NCT06586515

Eli Lilly and Company

2 February 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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