This study is for men with high-risk prostate cancer. It compares stereotactic body radiation therapy (SBRT), which is a special type of radiation that targets tumors more precisely, to the usual radiation therapy. SBRT involves 5 treatments in 2 weeks, while the usual therapy may take 20-45 treatments over 4-9 weeks. The goal is to see if less radiation with SBRT can stop cancer from coming back as well as the longer treatment.
Primary Objective: To compare how long patients live without the cancer spreading, using regular imaging tests, between those receiving SBRT and those getting the usual radiation.
- Study Duration: Patients are followed every 6 months for 5 years.
- Treatment Options: SBRT (5 treatments in 2 weeks) vs. usual radiation (20-45 treatments in 4-9 weeks).
- Participation Requirements: Includes five visits for treatment and regular follow-ups.
To participate, patients must be 18 or older and have specific prostate cancer characteristics. No previous prostate surgery or overlapping radiation treatment is allowed. This study aims to make treatment shorter and possibly easier for patients while still being effective.