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A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Long-term study for age-related macular degeneration treatment research.

Recruiting
60 years and older
All
Phase 2

This study looks at the long-term safety of a treatment called **JNJ-81201887** for people with **Geographic Atrophy (GA)**, a condition that causes vision loss due to **Age-related Macular Degeneration (AMD)**. People who were part of earlier studies and received this eye treatment or a fake treatment (sham) can join. The treatment involves an **intravitreal injection**, which means a shot is given directly into the eye. This study will help researchers see how safe this treatment is over time. There are no special rules to stop someone from joining this study, but you have to sign a paper saying you understand what the study is about and agree to be part of it.

  • Participants must have been part of previous related studies.
  • No need for women or partners to use birth control for this study.
  • Must sign a consent form to join the study.
Study details
    Geographic Atrophy
    Macular Degeneration

NCT06635148

Janssen Research & Development, LLC

9 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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