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Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Studying Retatrutide's effects on diabetes with kidney issues and insulin use.

Recruiting
18 years and older
All
Phase 3

This study aims to see how well a new drug, Retatrutide, works for people with *Type 2 Diabetes* who have kidney problems and are not controlling their blood sugar well with their current medicine. *Type 2 Diabetes* is when your body doesn't use insulin well. Insulin helps sugar get from your blood into your cells for energy. Renal impairment means your kidneys aren't working as they should. The study compares Retatrutide to a placebo (a pill with no medicine in it). Some people in the study will keep taking their usual medicine, like insulin, *metformin* (a diabetes medicine), or *SGLT2 inhibitors* (which help remove sugar through urine). The study lasts about 14 months and includes around 22 doctor visits.

  • The study lasts about 14 months with up to 22 visits.
  • Participants will receive either Retatrutide or a placebo.
  • Participants must have Type 2 Diabetes and kidney problems.
Study details
    Type 2 Diabetes

NCT06297603

Eli Lilly and Company

2 March 2025

Step 1 Get in touch with the nearest study center
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