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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

Trial studying Pozelimab and Cemdisiran for Geographic Atrophy in adults.

Recruiting
50 years and older
All
Phase 3

This study is testing new drugs, pozelimab and cemdisiran, for adults with geographic atrophy (GA). GA is a condition caused by age-related macular degeneration (AMD), which affects the central part of the vision. The goal is to see if these drugs, alone or together, can slow down GA compared to a placebo (a treatment with no active drug). Researchers also want to know about possible side effects, how much drug enters the blood, and if the body creates antibodies against the drugs.

  • The study involves injections and regular clinic visits.
  • Participants must be willing to get specific vaccinations.
  • There are specific criteria for who can join, like not having other eye diseases.

To join, participants need to have GA due to AMD, meet vision requirements, and agree to follow all study procedures, including vaccinations. They cannot join if they have other eye conditions or have had certain treatments recently. The study aims to find safe and effective treatments for this eye condition.

Study details
    Age-related Macular Degeneration (AMD)
    Geographic Atrophy (GA)

NCT06541704

Regeneron Pharmaceuticals

16 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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