This study tests a new medicine called **lunsekimig** for people with **chronic rhinosinusitis with nasal polyps (CRSwNP)**. This is an ongoing nose and sinus issue with growths inside the nose. People who join this study will get either lunsekimig or a placebo, which is a fake treatment, to compare how well the real medicine works. The study is **double-blind**, meaning neither the doctors nor the patients know who gets the real medicine. It's for adults aged 18-70 whose current nose spray treatment isn't working well enough. The study lasts about 40 weeks (almost 10 months) and includes a screening period, treatment, and follow-up. Participants may have **asthma**, and their lung function will be checked.

• The study lasts about 40 weeks.
• Participants will receive either the new medicine or a placebo.
• Eligibility includes having nasal polyps despite current treatment.

Participants should not have had recent nasal surgery, certain infections, or other specified health issues. Always consult with a healthcare provider to understand the potential benefits and risks of joining a clinical study.