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Phase 1/2 Study of BDTX-1535 in Patients with Glioblastoma or Non-Small Cell Lung Cancer with EGFR Mutations

Study testing BDTX-1535 for glioblastoma and lung cancer with EGFR mutations.

Recruiting
18 years and older
All
Phase 1/2
This study focuses on a new drug, **BDTX-1535**, to treat *glioblastoma* (a type of brain cancer) and **non-small cell lung cancer (NSCLC)** with specific *epidermal growth factor receptor (EGFR)* mutations. The study is divided into two phases. Phase 1 is complete, while Phase 2 is open for enrollment. Patients will take the drug by mouth in 21-day cycles. The study aims to find the safest dose and see how the drug works in the body and against cancer. **Key points to consider:** - **Study Length & Visits**: Participation involves taking the medication at home and regular check-ups. - **Eligibility**: Must have advanced NSCLC with specific EGFR mutations or glioblastoma. - **Risks & Benefits**: Understand potential side effects and possible benefits of trying a new treatment. Participants need to have a confirmed diagnosis of NSCLC or glioblastoma and must meet specific criteria related to past treatments and current health status. Some conditions such as certain prior treatments, other health issues, or active infections could exclude participation. If considering this study, discuss with your doctor to understand all the details and implications.
Study details
    Non-Small Cell Lung Cancer
    Advanced Non-Small Cell Squamous Lung Cancer
    Metastatic Lung Non-Small Cell Carcinoma
    Metastatic Lung Cancer
    NSCLC
    Advanced Lung Carcinoma
    Epidermal Growth Factor Receptor C797S
    Epidermal Growth Factor Receptor G719X
    EGF-R Positive Non-Small Cell Lung Cancer
    EGFR-TKI Resistant Mutation

NCT05256290

Black Diamond Therapeutics, Inc.

8 February 2025

Step 1 Get in touch with the nearest study center
Entire USA
Results (1 sites found)
  • 1

    Emory Winship Cancer Center

    Atlanta GA United States

You are contacting

Investigator Avatar
Ashley Trumball

Primary Contact

site
Emory Winship Cancer Center

Atlanta GA United States

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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