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A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Testing Dazodalibep in Sjögren's Syndrome with significant symptoms.

Recruiting
18 years and older
All
Phase 3

This study is testing a new medicine called dazodalibep for people with Sjögren's Syndrome (SS). Sjögren's Syndrome is a disease where the body's immune system attacks its own healthy cells, causing dry mouth and eyes. The study will see if dazodalibep helps people who have moderate-to-severe symptoms, which means their symptoms are more serious. It will also check if the medicine is safe and how patients feel when taking it through surveys called Patient Reported Outcomes (PROs). To join, you must have been diagnosed with SS and have a certain score from a test called the ESSDAI. This score shows how active the disease is. You also need to test positive for specific antibodies in your blood.

Do not join if you had major blood clots or certain cancers in the past few years. The study will not include any severe heart conditions either. It's important to know that this study could involve some risks from the new medicine.

  • Study involves taking dazodalibep and reporting your condition.
  • Check if you meet the health requirements before joining.
  • Understand the potential risks and benefits.
Study details
    Sjogren's Syndrome

NCT06104124

Amgen

16 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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