Study Overview: This study is testing a new drug, BHV-1510, for people with serious solid tumors, which are growths that happen when cells in the body grow uncontrollably. It's for patients who have already tried other treatments. The trial has two parts: Phase 1 checks safety and Phase 2 tests how well the drug works. BHV-1510 is used alone or with another drug called cemiplimab.
Who can join? Adults 18+ with advanced tumors that cannot be removed or cured can participate. Participants should have tried standard treatments before. They need to be in good general health and not have certain health problems like significant lung or eye diseases.
Who cannot join? Pregnant women, those with active brain problems, or people who need oxygen daily cannot join. Also, if you've had major surgery recently or a reaction to similar drugs, you might not qualify.
- The study might take several months, and you may need to visit multiple centers.
- Participants might experience side effects from the drugs.
- There may be no direct benefit, but your participation could help future patients.