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A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

Examining two doses of Amlitelimab for moderate-to-severe eczema patients.

Recruiting
12 years and older
All
Phase 3

This study is for people aged 12 and older with moderate-to-severe atopic dermatitis (AD). Atopic dermatitis is a skin condition that makes skin red and itchy. The study looks at how well a medicine called amlitelimab works when given under the skin.

  • **Study Length:** Up to 64 weeks. This includes 48 weeks of treatment and a 16-week safety follow-up.
  • **Visits Needed:** Up to 14 visits to the study center.
  • **Eligibility:** Must have been part of a previous study with amlitelimab and be at least 12 years old.

The study compares two amlitelimab doses. Participants are those who responded well in past studies. They'll either keep the same dose, switch doses, or stop treatment to see if their condition stays the same. The study is "double-blind," meaning neither the participants nor the researchers know who is receiving which dose. This helps ensure fair results. Some people may not be allowed if they have certain health problems or didn't follow rules in past studies. This is a chance to join research that might help improve treatments for AD. Before joining, it's important to discuss with your family and doctor to make sure it's right for you.

Study details
    Dermatitis Atopic

NCT06407934

Sanofi

16 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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