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A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Comparing MEZIVd and PVd treatments for relapsed multiple myeloma.

Recruiting
18 years and older
All
Phase 3

Multiple Myeloma is a type of cancer that affects the blood. This study is testing two different drug combinations to see which works better for patients whose cancer has returned after treatment. One combination is called MeziVd, which includes mezigdomide, bortezomib, and dexamethasone. The other is PVd, which includes pomalidomide, bortezomib, and dexamethasone.

For this study, you need to have tried 1 to 3 other treatments for multiple myeloma before and received lenalidomide. You should also have a certain level of a protein called M-protein in your blood or urine, which helps confirm the diagnosis.

  • **Study Length:** Participation involves multiple visits over a period of time.
  • **Eligibility:** Check if you have had the right number of treatments before and can meet other health criteria.
  • **Safety:** The study compares the safety of the drug combinations, but there might be risks, so discuss with your doctor.

If you're interested in participating, make sure you meet the criteria and discuss the potential risks and benefits with your healthcare provider. Always consult your doctor before joining any clinical study.

Study details
    Relapsed or Refractory Multiple Myeloma

NCT05519085

Celgene

2 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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