Vitiligo is a skin condition where patches of skin lose color. This study, called CUV105, will test if a medicine called afamelanotide (a-fuh-mel-ah-no-tide) combined with special light therapy called Narrow-Band Ultraviolet B (NB-UVB) is better for treating vitiligo than just using the light therapy alone. Afamelanotide helps darken the skin and NB-UVB light helps with skin color changes.

To join this study, you must be at least 12 years old and have vitiligo in certain areas of your body. You cannot join if you've used similar treatments recently, have certain skin conditions, or are pregnant.

• This study involves using both a medicine and light therapy, or just light therapy.
• Make sure you haven't had certain treatments for vitiligo recently if you want to join.
• If you are pregnant or have certain skin issues, you cannot participate.