Image

A Study of TYRA-300 in Children With Achondroplasia: BEACH301

Exploring TYRA-300 for children with achondroplasia in BEACH301 study.

Recruiting
3-10 years
All
Phase 2

TYRA-300 Study is for children aged 3 to 10 with a condition called achondroplasia, which affects growth. The study checks if a drug called TYRA-300 is safe and helps children grow better. TYRA-300 targets a specific protein in the body called FGFR-3 to help with bone growth. To join, children must have open growth plates, which means their bones are still growing. They also need to be able to walk by themselves and take medicine by mouth.

Three groups will be studied: Sentinel Safety Cohort (ages 5-10), Cohort 1 (ages 3-10, no prior growth therapy), and Cohort 2 (ages 3-10, with prior growth therapy). Children with diseases affecting growth or certain eye conditions can't join. This study will take place in multiple centers, and it's important for parents to consent for their child to participate.

  • The study involves multiple visits.
  • Participation is voluntary and requires parental consent.
  • Potential benefits include improved growth, but risks are also possible.
Study details
    Achondroplasia

NCT06842355

Tyra Biosciences, Inc

9 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.